Release date: 2014-02-27
When Acupuncture was first popular in the Western Hemisphere, it was questioned. Now such doubts still exist. But over time, through careful observation, scientists have obtained real evidence that the ancient Chinese practitioners of the medical art really recognized something important (free trial of MP Biomedicals mycoplasma removal reagents).
Now, a new study confirms the direct link between the use of acupuncture therapy and some of the physical processes that alleviate sepsis. Sepsis is a disease caused by infections and inflammation, often in hospital intensive care units, which causes approximately 250,000 deaths each year in the United States. Related papers were published in the February 23 issue of Nature Medicine.
Luis Ulloa, an immunologist at the University of New Jersey School of Medicine at Rutgers University, said: "Sepsis is a major cause of death in hospitals. But in many cases patients are not killed by infection. They are formed after infection. I die from inflammatory diseases. So we hope to study how to control inflammatory diseases."
Researchers already know that one of the main nerves that stimulate the body: the vagus nerve can touch some processes in the body to reduce inflammation, so they want to see if a small amount of current is transmitted through the vagus nerve or other nerves in an acupuncture form, and it is possible to alleviate the septicemia in mice. Inflammation and organ damage. Ulloa explained that increasing the current can amplify the effects of acupuncture, and that electrotherapy has been approved by the FDA for the treatment of pain in human patients.
When the researchers applied electroacupuncture to septic mice, it was found to stimulate cytokines that help limit inflammation as expected, and half of the mice survived for at least a week. Mice without acupuncture have a zero survival rate.
Ulloa and his team then conducted further detailed investigations to clarify the reasons for the success of acupuncture. But they generated a very disappointing research finding on the surface. They found that when they removed the adrenal gland (the endocrine organ that produces hormones in the body), the electroacupuncture did not work. The study found a large obstacle to the use of acupuncture to treat human sepsis, as most cases of human sepsis have a sharp decline in adrenal function. In theory, electroacupuncture may still help a small number of patients with good adrenal function, but not for a large number of other patients.
The researchers conducted a more in-depth study and found some specific anatomical changes that occurred when electroacupuncture was performed with a normal functional adrenal gland. These changes include elevated levels of dopamine. Dopamine is a substance that plays an important role in the immune system. But they found that dopamine alone did not inhibit inflammation. They then used some of the most positive effects of a combination of fenoldopam instead of simulated dopamine, which succeeded in reducing sepsis-related deaths by 40% without acupuncture.
Ulloa believes that these results have a double meaning.
On the one hand, this research goes beyond the physical evidence that showed the value of acupuncture. His results show that acupuncture has potential benefits not only for sepsis but also for the treatment of other inflammatory diseases such as rheumatoid arthritis, osteoarthritis and Crohn's disease.
On the other hand, by establishing a drug that can reduce sepsis death in mice, he provides an innovative circuit diagram for the development of potential drugs. Since no drugs are currently approved by the FDA for sepsis treatment, this roadmap may be of paramount importance.
Ulloa said: "I don't know that the best treatment for sepsis in the future will be electroacupuncture or some analog electroacupuncture. But the bottom line is that this research has opened the door to both."
Source: Contemporary Health News
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