Release date: 2015-05-19
For a long time, one of the dreams of science fiction is to build the flesh, such as the hand of Luke Skywalker in Star Wars, and the red-haired female Lilu in The Fifth Element. With 3D printing, reality has not caught up with fantasy, but with bio 3D printing, the situation is different, it is the printing of body tissue. Recently, researchers at the Michigan Institute of Technology developed a small biological 3D printer that can be used to print artificial nerve tissue.
Tuluo Sukufa, associate professor of mechanical engineering and biomedical engineering at the Michigan Institute of Technology's Nanomedicine and Nanoelectronics Laboratory, said that nerve regeneration is a biomedical engineering problem. "We have all the nerve cells at birth and have been carrying them all the time. Once the nerve cells are damaged, they can't recover well." But now, nanotechnology biomimetic materials can help patients with spinal cord injuries and regenerate their damaged nerves.
Some devices have been able to print the entire organ with great precision, but they are as large as a room and placed between the cell culture hood, the incubator and the refrigerator. Researchers want to make these huge devices small and flexible, just like their small printers.
According to a recent report by the Physicist Network, the small 3D printer developed by researchers at the Michigan Institute of Technology can be placed on an old-fashioned desk, like a toaster with the front cover and sides removed, and a stainless steel disc. Surrounded by a metal frame, it is illuminated by UV light with a hydraulic system and piping on the back. There is a large syringe in the printer "ink cartridge" with a red gelatinous liquid. Just attach the needle printhead to it and take out the computer and print the tissue holder.
The key to printing is to have the right "bio-ink" to print the tissue. The nerve needs biocompatible tissue as a cell scaffold, and cell membrane nanocrystals have excellent mechanical properties and are very suitable. In addition, the function of the nerve is to transmit electrical impulses, and the stent must be electrically conductive. To this end, researchers added graphene to the printed materials to create a biocompatible graphene-binding polymer that melts into a gel that can quickly flow out under printing pressure.
The researchers said they will study a streamlined and applicable method for printing nerve cells. At the same time, they also hope that the materials developed will have a wider range of uses, not just nerve regeneration.
Source: Technology Daily
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