According to reports, researchers have taken a big step forward in the study of soil bacteria. They successfully sequenced more than 6,000 genes for this mysterious and deadly pathogen, helping to solve the mechanism of the disease in the human body. In other words, researchers are expected to develop better diagnostic instruments, treatment programs, and vaccines against the disease in the near future. Responsible for completing the gene sequencing of this pathogen (scientific name is burkholderia pseudomallei) is the Wellcome Trust Sanger Institute in Cambridge, UK. Singaporean scientific researchers also actively participated in the "bottom uncovering" of this mystery germ. work. The National Institute of Defense Medicine and Environment (DMERI@DSO) under the Singapore Institute of Defense Science and Technology is responsible for arranging all the discovered genes on the microarray chip, allowing researchers to once go through the whole genome of the bacteria, rather than hardships. Analyze and test each gene one by one. Currently, researchers only understand the functions of two-thirds of these genes. Now that they have microarray chips for soil bacteria, they will be able to simultaneously test the response of an antibiotic to all 6000 genes and thus be more accurate. Understand the impact of individual genes on the function of germs. Professor Pingping Zhang, director of the Molecular Genetics Laboratory at the National Defense Medical Research Institute, points out that this will narrow the scope of bacterial antibody research because if they can use the chip to find genes that make the bacteria more virulent, they can target those genes. , Developed antibodies that can effectively deal with the bacteria. The so-called soil disease refers to a disease that is caused by contact with contaminated water and soil. The name of the disease is called nasal discharge. The cause of the disease is still unknown in the medical community. Symptoms include: fever, cough, chills, shortness of breath, fatigue, and joint or chest pain. A person who has been invaded by the genus Inoshelum will develop on two days or several years later. Boar-like diseases have attracted the attention of national defense agencies, mainly because the US Center for Disease Control and Prevention (CDC) in Atlanta has listed it as one of the bacteria that can be used to make biochemical weapons. In the first four months of this year, there was a rare wave of mud in the local area. As of April 3, a total of 31 people became ill and 15 of them died of illness. The peak of the disease appeared in 1998, when 114 people were infected and 19 died. Associate Professor Li Jinfu, director of the National Institute of Defence Medicine and Environment under the National Defense Science and Technology Research Institute, pointed out that as long as the diagnosis and treatment can be diagnosed and treated as soon as possible, the infected person still has a great chance of recovery, so constantly improve the diagnosis methods of the bacteria to prevent and treat these diseases. There is great significance. The National Defense Science and Technology Research Institute took charge of hosting the Meloidosis Congress this year, providing a platform for national experts to share research results. This kind of rhinorrhea-like research meeting held once every three years has entered the fourth session, this time for the first time in our country. Nearly 200 experts from 16 countries around the world are currently gathering locally for a three-day seminar. Experts describe the best way to deal with snot (soil disease). The name of soil disease is called melioidosis (soil disease). It is a disease caused by bacteria that are often found in surface water and mud. I like to grow in particular. In humid soils of tropical countries, like rice fields and mud. Therefore, the soil-infected zones are mainly tropical countries such as Southeast Asia, northern Australia, and southern North America. Rhinorrhoea is common in Southeast Asia and the cases are mainly concentrated in Vietnam, Myanmar and Malaysia. Northern Australia is also an area of ​​popularity. Experts say that sheep, goats, horses, pigs, cattle, dogs, cats and other animals are also like nosebleeds and can be transmitted to human-like diseases. Skin wounds or abrasions on human skin may be contaminated with soil if they come into contact with contaminated soil or water. People may also be infected by inhalation of contaminated soil dust and swallowing or inhaling contaminated water. Infections between people are very rare. The germs enter the body and cause abscesses and blood poisoning. People who are infected may have symptoms of fever, cough, and difficulty breathing. Some patients develop pneumonia. Once the patient is found to have fever, cough, chest pain, or local abscess, he or she will be suspected of having a soil disease and given proper treatment as soon as possible. Symptoms include: fever, cough, chills, shortness of breath, fatigue, and joint or chest pain. A person who has been invaded by the genus Inoshelum will develop on two days or several years later. Boar-like diseases have attracted the attention of national defense agencies, mainly because the US Center for Disease Control and Prevention (CDC) in Atlanta has listed it as one of the bacteria that can be used to make biochemical weapons. In the past 10 years, Singapore has found 36 to 114 different cases of soil diseases every year, with an average of 67 cases each year. In the first 7 months of this year, there have been 57 cases. According to the Singapore Ministry of Health’s analysis of 135 cases from 2001 to 2003, the patients with soil disease had 2 to 96 years of age. The overall prevalence rate was 1.6 per 100,000 people, but the older the disease, the more The higher the chance, 40% of the 100,000 people who are over the age of 55 may suffer from soil disease. In addition, the probability of Malay suffering from soil diseases is 2.1 per 100,000 people, which is higher than the Chinese (1 per 100,000) and the Indian (1.7 per 100,000). The best way to deal with contagious diseases such as soil diseases is to train local epidemiologists to conduct investigations more thoroughly, because doctors can only be more effective by thoroughly understanding how the soil disease attacks the human body and how it spreads. Help people prevent this disease. Preventive measures Persons engaged in a number of industries, such as military personnel, site workers, cleaners and car drivers, are generally more likely than ordinary people to infect soil diseases. Therefore, appropriate preventive measures must be taken. In addition, construction workers, service personnel, students, and people who often go outdoors should also be prevented. The best way to prevent infection is to use a waterproof bandage to cover all scraped skin or wounds, or to put on waterproof boots and waterproof gloves before touching watery soil. There is currently no vaccine against this bacteria, but if it is detected early, it can be treated with antibiotics. Only one saliva sample is needed to confirm the diagnosis. Singapore's snot has caused 24 deaths. According to Reuters news, Singapore’s health department announced on Friday that an indigenous bacterial virus known as snot has caused 24 Singaporean deaths this year, and its 40% mortality rate It is even more terrible than SARS and bird flu. The bacterium was listed as a potential biological weapon by the U.S. government, but the Singaporean government stated that there is no indication that the bacterium has spread internationally. When the scraped skin has direct contact with contaminated soil or water, the bacteria will enter the body, causing abscesses and blood poisoning. People who are infected may have symptoms of fever, cough, and difficulty breathing. Some patients develop pneumonia. According to Singaporean government agencies, from January to July this year, 40% of the patients infected with this bacterium died. The rate of death from atypical pneumonia was 13%. By the beginning of September, 79 people had been diagnosed with the bacteria. Because this virus is a potential biological weapon, so many infected people have caused the Singapore government to investigate whether anyone has intentionally spread the virus. But so far there is no evidence that the bacteria are man-made. There is currently no vaccine against this bacteria, but if it is detected early, it can be treated with antibiotics. Only one saliva sample is needed to confirm the diagnosis. Rhinorrhoea is common in Southeast Asia and the cases are mainly concentrated in Vietnam, Myanmar and Malaysia. Northern Australia is also an area of ​​popularity. Experts say that sheep, goats, horses, pigs, cattle, dogs, cats and other animals are also like nosebleeds and can be transmitted to human-like diseases.
Pharmaceutical Process Contamination Control Products
Cleanroom Consumables, Personal Protective Equipment ,Clean Disinfection Products , Clean Detergents
AUSTAR Goup , https://www.hansencleanroom.com