Introduction to colloidal gold technology
Related definition
The immunocolloidal gold technique uses colloidal gold as a tracer and immunologically highly specific antigen-antibody reaction as the basis for immunolabeling.
Technological development
1. Rapid immunogold filtration method (80s)
It consists mainly of two parts: a membrane percolator and a labelled combination. The former is a plastic small box filled with a water-absorbing substance, and a nitrocellulose membrane adsorbed with an antibody (for example, a double antibody sandwich method) is placed on the surface, and the labeled conjugate is an immunogold.
2. Immunochromatography (90s)
In the immunochromatography, the sample solution dropped at one end of the membrane is subjected to capillary action (cross-flow based on chromatography) to the other end. During the movement, the analyte is immobilized by binding to a receptor (antigen or antibody) immobilized on a certain region of the membrane, and the unrelated substance is separated beyond the region, and then the color of the marker is used to determine the test result.
Standard reagent strip schematic
Advantages and disadvantages
application
TSR-100 colloidal gold reader
The TSR-100 colloidal gold reader is used for the detection of samples of colloidal gold immunochromatographic test strips. By detecting the color depth changes of gold standard test papers, the content of the detected items is qualitatively and quantitatively analyzed to avoid human interpretation. Subjective error. And provide test results quickly, with high accuracy and repeatability.
Features
- Establish test curves for quantitative analysis
- For different test strips, customized on demand, and provide a complete solution for R&D-production-quality control-client
- Accurately identify CT line position, the result is more reliable
- Powerful software system for different test strips
- 2 sets of embedded software: 1 set of end customers, 1 set of reagent manufacturers
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