Nature: The maximum life expectancy of human beings is 125 years old, and it is impossible to continue to increase.

Nature: The maximum life expectancy of human beings is 125 years old, and it is impossible to continue to increase.

October 08, 2016 Source: Bio Valley

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In a new study, researchers from the Albert Einstein College of Medicine in the United States suggested that it might not be possible to extend human life beyond the age at which the longest-lived person has survived. The relevant research results were published online in the Nature Journal on October 5, 2016, and the paper titled "Evidence for a limit to human lifespan".

Since the nineteenth century, the average life expectancy of humans has continued to rise almost steadily due to improvements in public health, diet, environment and other areas. For example, compared to the average life expectancy of Americans born in 1900, which is only 47 years old, the life expectancy of Americans born today is expected to be close to 79. Since the 1970s, the longest lifespan of mankind, the age of the longest-lived person, has also risen. But according to researchers at the Albert Einstein College of Medicine, there is an upper limit to the upward trend in human longevity, and we have reached this limit.

Dr. Jan Vijg, professor of ophthalmology and visual science at the Albert Einstein College of Medicine, said that “the demographers and biologists have been claiming that there is no reason to believe that the continued increase in human longevity will be rapid. End. But our data strongly suggests that it has reached the upper limit, and this happened in the 1990s."

Dr. Vijg and his colleagues analyzed data from the Human Mortality Databas, which collects mortality and demographic data from more than 40 countries. Since 1900, these countries have generally experienced a decline in late-life mortality. The proportion of each birth generation (ie, a person born in a particular year) to old age (defined as 70 years and older) increases with their birth year, indicating that the average life expectancy of humans continues to increase.

But when the researchers studied the improvement in survival for people aged 100 and older since 1900, they found that no matter what year the person was born, the improvement in survival peaked at around 100 years and then quickly declined. Dr. Vijg said, "This finding suggests that the effect of reducing old-age mortality is decreasing, and that human life may be limited."

Dr. Vijg and his colleagues then studied the “highest reported age of death” from the International Database on Longevity. They focused on the four countries with the highest number of longevity (US, France, Japan, and the United Kingdom) who were verified to live to be 110 or older between 1968 and 2006. The death age of these supercentenarians increased rapidly between the 1970s and the early 1990s, but peaked around 1995 - further evidence suggests that human life limits . The researchers noted that this peak occurred near 1997, the year when the 122-year-old French woman Jeanne Calment died, the longest-lived person ever recorded.

Using the highest age of death reported in these reports, the researchers set the average longest life of humans at 115 years old -- a calculation that allows the recorded elderly to have an occasional lifespan that is longer or shorter than 115 years. (They concluded that Jeanne Calment is a statistically abnormal person.) Ultimately, the researchers calculated the age of 125 as the absolute upper limit of human life. In other words, this means that in a given year, the probability of seeing a person living to 125 in any place in the world is less than one in ten thousand.

Dr. Vijg said, " Further progress in combating infectious diseases and chronic diseases may continue to increase the average life expectancy of humans, but it will not increase the longest lifespan of humans. Although imagining a breakthrough in treatment may extend human life beyond what we have calculated. Limitations, but these advances need to overcome many of the genetic variations that seem to determine the overall lifespan of humans. The resources that are being consumed today to increase lifespan should probably lead to a prolonged healthspan, a period of good health in old age. ”

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