Researchers explore new methods for detecting human body clocks

Researchers explore new methods for detecting human body clocks

January 15, 2019 Source: Xinhuanet

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Some people are "early birds", others are "night owls", and everyone has their own unique biological clock. At present, multinational researchers are trying to develop new methods for rapid detection of the human body clock, in order to better understand the human body and ensure health.

The biological clock is a system that controls the daily biological rhythm in the human body. It helps regulate about 40% of the human body's genetic activities. The "rhythm arrangement" of sleep, eating, body temperature and blood pressure are all related to it. A common method of measuring the body clock is to monitor changes in melatonin concentration in the human body. However, this method requires the subject to stay in the dark room for a long time, collecting blood or saliva samples every about one hour.

In the new issue of Scientific American magazine, in order to develop more convenient, accurate and inexpensive detection methods, three teams in the world are currently studying how to evaluate genetic activity by measuring changes in blood ribonucleic acid. Use machine learning algorithms to calculate which genes are better able to reveal human rhythms.

At present, the testing method developed by the team led by Achim Kramer of the University Hospital of Saritaire in Germany is very close to clinical application. The difference between the results measured by this method and the results measured using melatonin is only within half an hour.

Researchers say that the circadian clock disorder is associated with many diseases such as diabetes, heart disease, and depression. If you can find a convenient way to detect the body's biological clock, it will help people better understand and treat these diseases.

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