Release date: 2015-10-08
Nervous system diseases have always been a problem that plagues medical workers. Among them, neuronal damage is an important cause of neurological diseases. Therefore, if you want to treat these diseases, how to repair damaged neurons becomes the number one problem facing scientists. Researchers such as the University of Minnesota and Princeton have found that 3D printing technology may play an unexpected role in this issue.
The scientists confirmed this idea in mouse experiments. They first used the 3D scan to obtain the contours of the mouse sciatic nerve, and then used 3D printing technology to create a silicone-based scaffold containing chemical components that promote neuronal regeneration. The researchers surgically implanted the stent into the injury site of the sciatic nerve of the mouse. After 10-12 weeks of culture, the impaired action function of the mouse was significantly improved.
Michael McAlpine, who participated in the study, said the results suggest that 3D printing technology can play an important role in promoting the recovery of complex neuronal functions. Although similar studies have shown that 3D printing technology can help linear neuron regeneration, it is the first time to use this technology to achieve the recovery of sensory and motor function of complex neurons such as sciatic neurons.
Neuronal regeneration is a complex process, and because of this complexity, neuronal damage caused by disease or injury is often lifelong. Next, the researchers hope to advance this approach to clinical research. If successful, this method will help more than 200,000 patients each year.
This research has been published in the latest issue of Advanced Functional Materials.
Source: Bio Valley
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